Provides specialist services, equipment packages and process solutions leading to improved protection of operators, reduction of cross-contamination and more efficient processing, thereby advancing occupational health and human healthcare.
The group is active in laboratory, medical and pharmaceutical equipment. Some of which are Biological Safety Cabinets, Laminar Hoods, CO2 Incubators, Ultra-low Temperature Freezers, Fume Hoods, IVF Incubators, Cleanrooms and Downflow Booths.
Dispense Booth
Dispensing booth is a kind of partial purifying equipment for filling, refilling, weighing and sampling of raw material and compounds. It is provided with HEPA filter, which prevents the airborne dusts by down draught technique. Dispensing booth is also called sampling booth or weighing booth.
Sampling booths
Dispensing & Sampling Booths are designed to give mixed air flow stream for product, operator and environmental protection and used to control the hazardous emissions of dust powder during powder dispensing/sampling process.
Solvent Booths
These are drum booths intended to provide low ppm containment during the transfer and handling of liquids, such as drum to drum transfer or drum to process reaction vessel. Thereby ensuring safety and security of personnel involved during transfer of substances
Downflow Booth
Downflow Booths are primarily used in the pharmaceutical industry to provide a safe working area for operators to protect them from hazardous, sensitizing, or toxic substances during manual handling of powders and solvents. These includes sampling and dispensing of materials and
Depending upon the application, two main configurations are used:
Re-circulatory booths are typically used for powder operations
Once-through booths are recommended where solvent or fume vapours are present.
RABS (Open)
An open operation RABS, by definition, provides recognition that the barrier doors can be opened for operator intervention(s), at defined risk assessed stages during aseptic production operations, after the last bio-decontamination step. Open operation RABs are further characterized:
Type 1: Process Intervention
(highest contamination risk)
Type 2: Set-up Intervention
(high contamination risk)
Type 3: Inherent Closed Barrier Interventions
(lowest contamination risk)
Open design RABs have an air handling system that is shared with the cleanrooms’ ceiling down flow with air an overspill to the surrounding environment. Overspill air is directed to a low level under the physical glove-barrier screens and below the points of critical operation, typically 300 mm below and away from the point of fill. Transfer devices may include closed or aerodynamic protection at the device-barrier connection location and maintain closed separation to the surrounding environment during the transfer procedure.
oRABS are used to incorporate filling line equipment both for aseptic and potent products processing. This equipment is a very practical to meet most of the containment solutions such as but not limited to milling and sieving containment purposes.
RABS (closed)
The closed RABS is an intermediate solution between isolators and open RABS. A closed operation RAB provides a higher level of contamination control because the RABs’ barrier doors remain closed from the point of the last bio-decontamination, through initial set-up through processing. These systems typically use transfer systems that are similar to isolator type transfer systems that are closed and dock with the RABs.
The system controls the full air flow (inlet and outlet), allowing the correct pressure to enter in the system thus making it is suitable to be used with slightly toxic products.
These systems cannot not be used for highly toxic products. However this can be considered as the right technology to be applied when a slightly potent/toxic product is to be manipulated.
Just like isolators, even closed RABS internally assure a “class A” environment, being the surrounding area classified as “class B”.
Closed design RABs have a dedicated air handling system that provides down-flow air that circulates inside physical barriers, together with the provision of fresh air make up and ducted exhaust systems. Materials transfer devices are either a fully closed system, (e.g. alpha-beta rapid transfer ports, and/or devices that connect or interface) are under aerodynamic barrier protection and remain closed to the surrounding environment during transfer procedures. Closed-design RABs may also include a gaseous decontamination system.
Applications
• Potent Filling Line Isolator
• Aseptic Formulation
• Contained powder handling
• Potent Formulation
Cabinets
Contained Powder Handling equipment is designed for a high level of operator protection by containing hazardous airborne powder. The airborne powders are well contained either inside the enclosure or the chambers and exhausted through a HEPA filter or direct to the laboratory exhaust. This is also specifically used during potent formulation because of the negatively pressure air.
Dynamics Passboxes
These are aseptic architectural systems with dynamic airflow that provides an air barrier to prevent contaminants from leaking into aseptic suits. They are utilized for aseptic transfer of materials into and out from the critical process environments.
Dynamic Pass Box assists in transfer of materials driven through a controlled environment but without much personnel movement. Furthermore, this box helps in prevention of contaminants entrance either in the clean room or between various classified areas.
Dynamic pass box need to be installed between two different classified area/rooms for material pass through. The purpose is to provide barrier between areas & to sweep away the particulate load if present on surface of object being transferred to more clean area.
Glove Box
Glovebox is the general term used to describe a sealed chamber that allows the operator to handle hazardous materials or agents having an unknown risk level. These units provide a controlled environment for working with samples while physically separating personnel from the materials they are manipulating. Gloveboxes serve the needs of a diverse range of industries. For example, the glove box is often utilized in biotechnology, biomedical, nuclear, defense, pharmaceutical, semiconductor and chemical applications. When these enclosures are used for microbiological research or to handle pathogens, they are referred to as Class III Biological Safety Cabinets. These units provide containment for work with high-risk biological agents and must be constructed in compliance with the Biosafety in Microbiological and Biomedical Laboratories (BMBL) specifications.
Aseptic Containment Isolator
An Aseptic Containment Isolator is a type of containment system designed for large volume sterility testing. It has a larger working area to accommodate various batch sizes and process flows. Aseptic Containment Isolator is the premium solution for handling pharmaceutical germ seed cells, aseptic cell processing and other containment solutions.
Applications
• Potent Filling Line Isolator
• Aseptic Formulation
• Potent Formulation
• Contained Powder Handling
• Offloading Containment Isolator
• Powder Sampling Isolator
• Sterility Testing Isolator
• Sub-division Isolators
Weighing & Dispensing Containment Isolators (WDCI)
Weighing and Dispensing Isolators are advanced containment systems providing controlled negative pressure environments to maximize personnel protection. This equipment is especially designed for weighing and dispensing of potent compounds, handling New Chemical Entities, and as containment solutions for compounds during sub-division and sampling processes.
Ceiling Laminar Airflow
Ceiling Laminar (Unidirectional) Airflow Unit is a containment equipment module for providing a zoned unidirectional downflow airflow. The purpose of this equipment is to provide laminar airflow to a working area or zone underneath it for protection of processes. Enhanced aseptic work zones are achieved by utilizing unidirectional airflow to positively pressurize and purge working environment from contaminants.
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